Start going towards the Airport Exit. Take US-101 North towards San Francisco. Take the I-380 West exit towards San Bruno I-280). Go 2 miles/3.2 kilometers. Take the I-280 North exit towards San Francisco. I-280 North becomes CA-1 North (19th Avenue). Stay on CA-1 and drive through Golden Gate Park. CA-1 North then becomes Park Presidio Drive. Go over Golden Gate Bridge. CA-1 North becomes US-HWY. 101 North. Stay on US-HWY. 101 North for approximately 65 miles/104 kilometers. Take the Central Healdsburg exit straight onto Healdsburg Avenue. Continue on Healdsburg Avenue to the center of town - the downtown Plaza, at Healdsburg Avenue and Matheson Street.
Google Directions: SFO --> Healdsburg
Also available is the Sonoma County Airport Express. Last stop is the Charles M. Schulz Sonoma County Airport (STS) in Santa Rosa (less than 10 miles/16 kilometers from Healdsburg). From there, many taxi services are available for transport from STS to Healdsburg.